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- Organs vary in their sensitivity not only to the amount of radiation dose they receive, but also to the distribution of that dose.
- Organs may be divided into subunits. Each subunit may be functional or non-functional following radiation damage.
- Subunits may be as small as cells or as large as lobes of the liver.
- Serial Organs are organs in which disabling any subunit causes the entire organ to fail.
- Parallel Organs are organs in which many or all of the subunits must be disabled to cause organ failure.
| Serial Organs | Parallel Organs |
| Spinal Cord | Lungs |
| Brain Stem | Liver |
| Optic Structures | Kidneys |
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